Maintenance of normal blood pressure is dependent on IP3R1-mediated regulation of eNOS

Endothelial cells (ECs) are critical mediators of blood pressure (BP) regulation, primarily via the generation and release of vasorelaxants, including nitric oxide (NO). NO is produced in ECs by endothelial NO synthase (eNOS), which is activated by both calcium (Ca(2+))-dependent and independent pat...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphovsmän: Yuan, Qi, Yang, Jingyi, Santulli, Gaetano, Reiken, Steven R., Wronska, Anetta, Kim, Mindy M., Osborne, Brent W., Lacampagne, Alain, Yin, Yuxin, Marks, Andrew R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2016
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968706/
https://ncbi.nlm.nih.gov/pubmed/27402766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1608859113
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