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Maintenance of normal blood pressure is dependent on IP3R1-mediated regulation of eNOS

Endothelial cells (ECs) are critical mediators of blood pressure (BP) regulation, primarily via the generation and release of vasorelaxants, including nitric oxide (NO). NO is produced in ECs by endothelial NO synthase (eNOS), which is activated by both calcium (Ca(2+))-dependent and independent pat...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Yuan, Qi, Yang, Jingyi, Santulli, Gaetano, Reiken, Steven R., Wronska, Anetta, Kim, Mindy M., Osborne, Brent W., Lacampagne, Alain, Yin, Yuxin, Marks, Andrew R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968706/
https://ncbi.nlm.nih.gov/pubmed/27402766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1608859113
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