Maintenance of normal blood pressure is dependent on IP3R1-mediated regulation of eNOS

Endothelial cells (ECs) are critical mediators of blood pressure (BP) regulation, primarily via the generation and release of vasorelaxants, including nitric oxide (NO). NO is produced in ECs by endothelial NO synthase (eNOS), which is activated by both calcium (Ca(2+))-dependent and independent pat...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Yuan, Qi, Yang, Jingyi, Santulli, Gaetano, Reiken, Steven R., Wronska, Anetta, Kim, Mindy M., Osborne, Brent W., Lacampagne, Alain, Yin, Yuxin, Marks, Andrew R.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2016
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968706/
https://ncbi.nlm.nih.gov/pubmed/27402766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1608859113
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