Nrf2 expression is increased in peripheral blood mononuclear cells derived from mild–moderate ex-smoker COPD patients with persistent oxidative stress

Inadequacy of antioxidant nuclear factor-E2-related factor 2 (Nrf2) and endoplasmic reticulum stress-mediated unfolded protein response has been implicated in severe chronic obstructive pulmonary disease (COPD) and cigarette smoking-induced emphysema. As evidence suggests that the ability to upregul...

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Detalhes bibliográficos
Publicado no:Int J Chron Obstruct Pulmon Dis
Main Authors: Fratta Pasini, Anna Maria, Ferrari, Marcello, Stranieri, Chiara, Vallerio, Paola, Mozzini, Chiara, Garbin, Ulisse, Zambon, Giorgia, Cominacini, Luciano
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968670/
https://ncbi.nlm.nih.gov/pubmed/27555763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/COPD.S102218
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