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Phase I study of palbociclib, a cyclin‐dependent kinase 4/6 inhibitor, in Japanese patients

This phase I study in Japanese patients evaluated the safety, pharmacokinetics, and preliminary efficacy of palbociclib, a highly selective and reversible oral cyclin‐dependent kinase 4/6 inhibitor, as monotherapy for solid tumors (part 1) and combined with letrozole as first‐line treatment of postm...

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Bibliographic Details
Published in:Cancer Sci
Main Authors: Tamura, Kenji, Mukai, Hirofumi, Naito, Yoichi, Yonemori, Kan, Kodaira, Makoto, Tanabe, Yuko, Yamamoto, Noboru, Osera, Shozo, Sasaki, Masaoki, Mori, Yuko, Hashigaki, Satoshi, Nagasawa, Takashi, Umeyama, Yoshiko, Yoshino, Takayuki
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968608/
https://ncbi.nlm.nih.gov/pubmed/26991823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12932
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