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Coming full circle: 70 years of chronic lymphocytic leukemia cell redistribution, from glucocorticoids to inhibitors of B-cell receptor signaling

Chronic lymphocytic leukemia (CLL) cells proliferate in pseudofollicles within the lymphatic tissues, where signals from the microenvironment and BCR signaling drive the expansion of the CLL clone. Mobilization of tissue-resident cells into the blood removes CLL cells from this nurturing milieu and...

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Bibliografske podrobnosti
izdano v:Blood
Main Authors: Burger, Jan A., Montserrat, Emili
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968370/
https://ncbi.nlm.nih.gov/pubmed/23264597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-08-452607
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