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Coming full circle: 70 years of chronic lymphocytic leukemia cell redistribution, from glucocorticoids to inhibitors of B-cell receptor signaling

Chronic lymphocytic leukemia (CLL) cells proliferate in pseudofollicles within the lymphatic tissues, where signals from the microenvironment and BCR signaling drive the expansion of the CLL clone. Mobilization of tissue-resident cells into the blood removes CLL cells from this nurturing milieu and...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Blood
Prif Awduron: Burger, Jan A., Montserrat, Emili
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Hematology 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968370/
https://ncbi.nlm.nih.gov/pubmed/23264597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-08-452607
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