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Structural basis of FYCO1 and MAP1LC3A interaction reveals a novel binding mode for Atg8-family proteins

FYCO1 (FYVE and coiled-coil domain containing 1) functions as an autophagy adaptor in directly linking autophagosomes with the microtubule-based kinesin motor, and plays an essential role in the microtubule plus end-directed transport of autophagic vesicles. The specific association of FYCO1 with au...

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Bibliografiske detaljer
Udgivet i:Autophagy
Main Authors: Cheng, Xiaofang, Wang, Yingli, Gong, Yukang, Li, Faxiang, Guo, Yujiao, Hu, Shichen, Liu, Jianping, Pan, Lifeng
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968224/
https://ncbi.nlm.nih.gov/pubmed/27246247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2016.1185590
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