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Molecular Structure of Aggregated Amyloid-β: Insights from Solid-State Nuclear Magnetic Resonance

Amyloid-β (Aβ) peptides aggregate to form polymorphic amyloid fibrils and a variety of intermediate assemblies, including oligomers and protofibrils, both in vitro and in human brain tissue. Since the beginning of the 21st century, considerable progress has been made to characterize the molecular st...

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Detalhes bibliográficos
Publicado no:Cold Spring Harb Perspect Med
Autor principal: Tycko, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968170/
https://ncbi.nlm.nih.gov/pubmed/27481836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a024083
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