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Advanced assessment of the physicochemical characteristics of Remicade® and Inflectra® by sensitive LC/MS techniques

In this study, we demonstrate the utility of ultra-performance liquid chromatography coupled to mass spectrometry (MS) and ion-mobility spectrometry (IMS) to characterize and compare reference and biosimilar monoclonal antibodies (mAbs) at an advanced level. Specifically, we focus on infliximab and...

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Опубликовано в: :MAbs
Главные авторы: Fang, Jing, Doneanu, Catalin, Alley, William R., Yu, Ying Qing, Beck, Alain, Chen, Weibin
Формат: Artigo
Язык:Inglês
Опубликовано: Taylor & Francis 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968138/
https://ncbi.nlm.nih.gov/pubmed/27260215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2016.1193661
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