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High-Sensitivity NanoLC—MS/MS Analysis of Urinary Desmosine and Isodesmosine

Chronic obstructive pulmonary disease (COPD) is characterized by the degradation of elastin, the major insoluble protein of lung tissues. The degradation of elastin gives rise to desmosine (DES) and isodesmosine (IDES), two major urinary products typified by a hydrophilic pyridinium- based cross-lin...

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Detalhes bibliográficos
Main Authors: Boutin, Michel, Berthelette, Carl, Gervais, François G., Scholand, Mary-Beth, Hoidal, John, Leppert, Mark F., Bateman, Kevin P., Thibault, Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787797/
https://ncbi.nlm.nih.gov/pubmed/19178285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac801745d
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