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High-Sensitivity NanoLC—MS/MS Analysis of Urinary Desmosine and Isodesmosine

Chronic obstructive pulmonary disease (COPD) is characterized by the degradation of elastin, the major insoluble protein of lung tissues. The degradation of elastin gives rise to desmosine (DES) and isodesmosine (IDES), two major urinary products typified by a hydrophilic pyridinium- based cross-lin...

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Библиографические подробности
Главные авторы: Boutin, Michel, Berthelette, Carl, Gervais, François G., Scholand, Mary-Beth, Hoidal, John, Leppert, Mark F., Bateman, Kevin P., Thibault, Pierre
Формат: Artigo
Язык:Inglês
Опубликовано: 2009
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787797/
https://ncbi.nlm.nih.gov/pubmed/19178285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac801745d
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