Comparison of Realistic and Idealized Breathing Patterns in Computational Models of Airflow and Vapor Dosimetry in the Rodent Upper Respiratory Tract

CONTEXT: Computational fluid dynamics (CFD) simulations of airflows coupled with physiologically-based pharmacokinetic (PBPK) modeling of respiratory tissue doses of airborne materials have traditionally used either steady-state inhalation or a sinusoidal approximation of the breathing cycle for air...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Inhal Toxicol
Prif Awduron: Colby, Sean M., Kabilan, Senthil, Jacob, Richard E., Kuprat, Andrew P., Einstein, Daniel R., Corley, Richard A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968083/
https://ncbi.nlm.nih.gov/pubmed/26986954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/08958378.2016.1150367
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