Comparative Risks of Aldehyde Constituents in Cigarette Smoke Using Transient Computational Fluid Dynamics/Physiologically Based Pharmacokinetic Models of the Rat and Human Respiratory Tracts

Computational fluid dynamics (CFD) modeling is well suited for addressing species-specific anatomy and physiology in calculating respiratory tissue exposures to inhaled materials. In this study, we overcame prior CFD model limitations to demonstrate the importance of realistic, transient breathing p...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Toxicol Sci
Κύριοι συγγραφείς: Corley, Richard A., Kabilan, Senthil, Kuprat, Andrew P., Carson, James P., Jacob, Richard E., Minard, Kevin R., Teeguarden, Justin G., Timchalk, Charles, Pipavath, Sudhakar, Glenny, Robb, Einstein, Daniel R.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Oxford University Press 2015
Θέματα:
Modeling of Aldehydes from Cigarette Smoke
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4476461/
https://ncbi.nlm.nih.gov/pubmed/25858911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfv071
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