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Tissue adaptation of regulatory and intraepithelial CD4(+) T cells controls gut inflammation

Foxp3(+) regulatory T cells in peripheral tissues (pT(regs)) are instrumental in limiting inflammatory responses to non-self antigens. Within the intestine, pT(regs) are located primarily in the lamina propria, while intraepithelial CD4(+) T cells (CD4(IELs)), which also exhibit anti-inflammatory pr...

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Библиографические подробности
Опубликовано в: :Science
Главные авторы: Sujino, Tomohisa, London, Mariya, Hoytema van Konijnenburg, David P., Rendon, Tomiko, Buch, Thorsten, Silva, Hernandez M., Lafaille, Juan J., Reis, Bernardo S., Mucida, Daniel
Формат: Artigo
Язык:Inglês
Опубликовано: 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968079/
https://ncbi.nlm.nih.gov/pubmed/27256884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaf3892
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