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LncRNA‐MIF, a c‐Myc‐activated long non‐coding RNA, suppresses glycolysis by promoting Fbxw7‐mediated c‐Myc degradation

The c‐Myc proto‐oncogene is activated in more than half of all human cancers. However, the precise regulation of c‐Myc protein stability is unknown. Here, we show that the lncRNA‐MIF (c‐Myc inhibitory factor), a c‐Myc‐induced long non‐coding RNA, is a competing endogenous RNA for miR‐586 and attenua...

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Bibliografiske detaljer
Udgivet i:EMBO Rep
Main Authors: Zhang, Pengfei, Cao, Limian, Fan, Pingsheng, Mei, Yide, Wu, Mian
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4967955/
https://ncbi.nlm.nih.gov/pubmed/27317567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201642067
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