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LncRNA‐MIF, a c‐Myc‐activated long non‐coding RNA, suppresses glycolysis by promoting Fbxw7‐mediated c‐Myc degradation

The c‐Myc proto‐oncogene is activated in more than half of all human cancers. However, the precise regulation of c‐Myc protein stability is unknown. Here, we show that the lncRNA‐MIF (c‐Myc inhibitory factor), a c‐Myc‐induced long non‐coding RNA, is a competing endogenous RNA for miR‐586 and attenua...

詳細記述

保存先:
書誌詳細
出版年:EMBO Rep
主要な著者: Zhang, Pengfei, Cao, Limian, Fan, Pingsheng, Mei, Yide, Wu, Mian
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4967955/
https://ncbi.nlm.nih.gov/pubmed/27317567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201642067
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