Follistatin‐like 1 promotes cardiac fibroblast activation and protects the heart from rupture

Follistatin‐like 1 (Fstl1) is a secreted protein that is acutely induced in heart following myocardial infarction (MI). In this study, we investigated cell type‐specific regulation of Fstl1 and its function in a murine model of MI. Fstl1 was robustly expressed in fibroblasts and myofibroblasts in th...

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Publicado en:EMBO Mol Med
Autores principales: Maruyama, Sonomi, Nakamura, Kazuto, Papanicolaou, Kyriakos N, Sano, Soichi, Shimizu, Ippei, Asaumi, Yasuhide, van den Hoff, Maurice J, Ouchi, Noriyuki, Recchia, Fabio A, Walsh, Kenneth
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4967946/
https://ncbi.nlm.nih.gov/pubmed/27234440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201506151
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