Vascular rarefaction mediates whitening of brown fat in obesity

Brown adipose tissue (BAT) is a highly vascularized organ with abundant mitochondria that produce heat through uncoupled respiration. Obesity is associated with a reduction of BAT function; however, it is unknown how obesity promotes dysfunctional BAT. Here, using a murine model of diet-induced obes...

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Bibliographic Details
Main Authors: Shimizu, Ippei, Aprahamian, Tamar, Kikuchi, Ryosuke, Shimizu, Ayako, Papanicolaou, Kyriakos N., MacLauchlan, Susan, Maruyama, Sonomi, Walsh, Kenneth
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4001539/
https://ncbi.nlm.nih.gov/pubmed/24713652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI71643
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