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NLRP3 protects alveolar barrier integrity by an inflammasome-independent increase of epithelial cell adherence
Bacterial pneumonia is a major cause of acute lung injury and acute respiratory distress syndrome, characterized by alveolar barrier disruption. NLRP3 is best known for its ability to form inflammasomes and to regulate IL-1β and IL-18 production in myeloid cells. Here we show that NLRP3 protects the...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4967923/ https://ncbi.nlm.nih.gov/pubmed/27476670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30943 |
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