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Treatment with an orally bioavailable prodrug of 17β-estradiol alleviates hot flushes without hormonal effects in the periphery

Estrogen deprivation has a profound effect on the female brain. One of the most obvious examples of this condition is hot flushes. Although estrogens relieve these typical climacteric symptoms, many women do not want to take them owing to unwanted side-effects impacting, for example, the uterus, bre...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Merchenthaler, Istvan, Lane, Malcolm, Sabnis, Gauri, Brodie, Angela, Nguyen, Vien, Prokai, Laszlo, Prokai-Tatrai, Katalin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4967894/
https://ncbi.nlm.nih.gov/pubmed/27477453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30721
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