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Sleep: A novel mechanistic pathway, biomarker, and treatment target in the pathology of Alzheimer's disease?
Sleep disruption appears to be a core component of Alzheimer's disease (AD) and its pathophysiology. Signature abnormalities of sleep emerge before clinical onset of AD. Moreover, insufficient sleep facilitates accumulation of amyloid-β (Aβ), potentially triggering earlier cognitive decline and...
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| Publicado en: | Trends Neurosci |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4967375/ https://ncbi.nlm.nih.gov/pubmed/27325209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tins.2016.05.002 |
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