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Cocaine Cardiovascular Effects and Pharmacokinetics after Treatment with the Acetylcholinesterase Inhibitor Donepezil

BACKGROUND: In rodents, cholinesterase inhibitors can cause sustained decreases in the reinforcing effects of cocaine. Nonetheless, cocaine is metabolized by butyrylcholinesterase (BuChE), raising concerns that cholinesterase inhibition could increase its peripheral concentrations, perhaps augmentin...

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Detalhes bibliográficos
Publicado no:Am J Addict
Main Authors: Grasing, Kenneth, Mathur, Deepan, DeSouza, Cherilyn, Newton, Thomas F., Moody, David E., Sturgill, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4967259/
https://ncbi.nlm.nih.gov/pubmed/27392137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajad.12402
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