Context-dependent effects of SOCS3 in angiotensin II-induced vascular dysfunction and hypertension in mice: mechanisms and role of bone marrow-derived cells

Carotid artery disease is a major contributor to stroke and cognitive deficits. Angiotensin II (Ang II) promotes vascular dysfunction and disease through mechanisms that include the IL-6/STAT3 pathway. Here, we investigated the importance of suppressor of cytokine signaling 3 (SOCS3) in models of An...

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Vydáno v:Am J Physiol Heart Circ Physiol
Hlavní autoři: Li, Ying, Kinzenbaw, Dale A., Modrick, Mary L., Pewe, Lecia L., Faraci, Frank M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2016
Témata:
Vascular Biology and Microcirculation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4967211/
https://ncbi.nlm.nih.gov/pubmed/27106041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00204.2016
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