Thyroid Hormone Receptor-β (TRβ) Mediates Runt-Related Transcription Factor 2 (Runx2) Expression in Thyroid Cancer Cells: A Novel Signaling Pathway in Thyroid Cancer

Dysregulation of the thyroid hormone receptor (TR)β is common in human cancers. Restoration of functional TRβ delays tumor progression in models of thyroid and breast cancers implicating TRβ as a tumor suppressor. Conversely, aberrant expression of the runt-related transcription factor 2 (Runx2) is...

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Detalhes bibliográficos
Publicado no:Endocrinology
Main Authors: Carr, Frances E., Tai, Phillip W. L., Barnum, Michael S., Gillis, Noelle E., Evans, Katherine G., Taber, Thomas H., White, Jeffrey H., Tomczak, Jennifer A., Jaworski, Diane M., Zaidi, Sayyed K., Lian, Jane B., Stein, Janet L., Stein, Gary S.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4967127/
https://ncbi.nlm.nih.gov/pubmed/27253998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2015-2046
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