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Visualizing recombination intermediates with single-stranded DNA curtains

Homologous recombination (HR) is a critical cellular process for repairing double-stranded DNA breaks (DSBs) – a toxic type of DNA lesion that can result in chromosomal rearrangements and cancer. During the early stages of HR, members from the Rad51/RecA family of recombinases assemble into long fil...

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Bibliografische gegevens
Gepubliceerd in:Methods
Hoofdauteurs: Qi, Zhi, Greene, Eric C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4967002/
https://ncbi.nlm.nih.gov/pubmed/27038747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2016.03.027
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