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Visualizing Protein Movement on DNA at the Single-molecule Level using DNA Curtains

A fundamental feature of many nucleic-acid binding proteins is their ability to move along DNA either by diffusion-based mechanisms or by ATP-hydrolysis driven translocation. For example, most site-specific DNA-binding proteins must diffuse to some extent along DNA to either find their target sites,...

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Main Authors: Silverstein, Timothy D., Gibb, Bryan, Greene, Eric C.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4111998/
https://ncbi.nlm.nih.gov/pubmed/24598576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2014.02.004
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