Cardiac Gene Expression Knockdown Using Small Inhibitory RNA-Loaded Microbubbles and Ultrasound

RNA interference has potential therapeutic value for cardiac disease, but targeted delivery of interfering RNA is a challenge. Custom designed microbubbles, in conjunction with ultrasound, can deliver small inhibitory RNA to target tissues in vivo. The efficacy of cardiac RNA interference using a mi...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Kopechek, Jonathan A., Carson, Andrew R., McTiernan, Charles F., Chen, Xucai, Klein, Edwin C., Villanueva, Flordeliza S.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4966949/
https://ncbi.nlm.nih.gov/pubmed/27471848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159751
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