Cardiac Gene Expression Knockdown Using Small Inhibitory RNA-Loaded Microbubbles and Ultrasound

RNA interference has potential therapeutic value for cardiac disease, but targeted delivery of interfering RNA is a challenge. Custom designed microbubbles, in conjunction with ultrasound, can deliver small inhibitory RNA to target tissues in vivo. The efficacy of cardiac RNA interference using a mi...

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Vydáno v:PLoS One
Hlavní autoři: Kopechek, Jonathan A., Carson, Andrew R., McTiernan, Charles F., Chen, Xucai, Klein, Edwin C., Villanueva, Flordeliza S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4966949/
https://ncbi.nlm.nih.gov/pubmed/27471848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159751
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