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When genome maintenance goes (badly) awry
Genetic abnormalities are present in all tumor types, although the frequency and type can vary. Chromosome abnormalities include highly aberrant structures, particularly chromothriptic chromosomes. The generation of massive sequencing data has illuminated the scope of the mutational burden in cancer...
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| Published in: | Mol Cell |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4966655/ https://ncbi.nlm.nih.gov/pubmed/27259208 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.05.021 |
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