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Understanding differences between synthetic and natural antibodies can help improve antibody engineering
Synthetic libraries are a major source of human-like antibody (Ab) drug leads. To assess the similarity between natural Abs and the products of these libraries, we compared large sets of natural and synthetic Abs using “CDRs Analyzer,” a tool we introduce for structural analysis of Ab-antigen (Ag) i...
Shranjeno v:
| izdano v: | MAbs |
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| Main Authors: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Taylor & Francis
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4966605/ https://ncbi.nlm.nih.gov/pubmed/26652053 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2015.1123365 |
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