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Oncogenes: The Passport for Viral Oncolysis Through PKR Inhibition

The transforming properties of oncogenes are derived from gain-of-function mutations, shifting cell signaling from highly regulated homeostatic to an uncontrolled oncogenic state, with the contribution of the inactivating mutations in tumor suppressor genes P53 and RB, leading to tumor resistance to...

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Détails bibliographiques
Publié dans:Biomark Cancer
Auteur principal: Fernandes, Janaina
Format: Artigo
Langue:Inglês
Publié: Libertas Academica 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4966488/
https://ncbi.nlm.nih.gov/pubmed/27486347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/BIC.S33378
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