Anticancer activity of TTAC-0001, a fully human anti-vascular endothelial growth factor receptor 2 (VEGFR-2/KDR) monoclonal antibody, is associated with inhibition of tumor angiogenesis

Vascular endothelial growth factor (VEGF) and its receptors are considered the primary cause of tumor-induced angiogenesis. Specifically, VEGFR-2/kinase insert domain receptor (KDR) is part of the major signaling pathway that plays a significant role in tumor angiogenesis, which is associated with t...

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Bibliographic Details
Published in:MAbs
Main Authors: Kim, Dong Geon, Jin, Younggeon, Jin, Juyoun, Yang, Heekyoung, Joo, Kyeung Min, Lee, Weon Sup, Shim, Sang Ryeol, Kim, Sung-Woo, Yoo, Jinsang, Lee, Sang Hoon, Yoo, Jin-San, Nam, Do-Hyun
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4966428/
https://ncbi.nlm.nih.gov/pubmed/26325365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2015.1086854
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