TTAC-0001, a human monoclonal antibody targeting VEGFR-2/KDR, blocks tumor angiogenesis

Angiogenesis is one of the most important processes for cancer cell survival, tumor growth and metastasis. Vascular endothelial growth factor (VEGF) and its receptor, particularly VEGF receptor-2 (VEGFR-2, or kinase insert domain-containing receptor, KDR), play critical roles in tumor-associated ang...

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Detalhes bibliográficos
Publicado no:MAbs
Main Authors: Lee, Weon Sup, Pyun, Bo-Jeong, Kim, Sung-Woo, Shim, Sang Ryeol, Nam, Ju Ryoung, Yoo, Ji Young, Jin, Younggeon, Jin, Juyoun, Kwon, Young-Guen, Yun, Chae-Ok, Nam, Do-Hyun, Oh, Keunhee, Lee, Dong-Sup, Lee, Sang Hoon, Yoo, Jin-San
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622656/
https://ncbi.nlm.nih.gov/pubmed/25942475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2015.1045168
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