Metformin Use and Survival of Patients With Pancreatic Cancer: A Cautionary Lesson

PURPOSE: The inclusion of metformin in the treatment arms of cancer clinical trials is based on improved survival that has been demonstrated in retrospective epidemiologic studies; however, unintended biases may exist when analysis is performed by using a conventional Cox proportional hazards regres...

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Vydáno v:J Clin Oncol
Hlavní autoři: Chaiteerakij, Roongruedee, Petersen, Gloria M., Bamlet, William R., Chaffee, Kari G., Zhen, David B., Burch, Patrick A., Leof, Emma R., Roberts, Lewis R., Oberg, Ann L.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Clinical Oncology 2016
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ORIGINAL REPORTS
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4966342/
https://ncbi.nlm.nih.gov/pubmed/27069086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2015.63.3511
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