E2f8 mediates tumor suppression in postnatal liver development

E2F-mediated transcriptional repression of cell cycle–dependent gene expression is critical for the control of cellular proliferation, survival, and development. E2F signaling also interacts with transcriptional programs that are downstream of genetic predictors for cancer development, including hep...

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Gepubliceerd in:J Clin Invest
Hoofdauteurs: Kent, Lindsey N., Rakijas, Jessica B., Pandit, Shusil K., Westendorp, Bart, Chen, Hui-Zi, Huntington, Justin T., Tang, Xing, Bae, Sooin, Srivastava, Arunima, Senapati, Shantibhusan, Koivisto, Christopher, Martin, Chelsea K., Cuitino, Maria C., Perez, Miguel, Clouse, Julian M., Chokshi, Veda, Shinde, Neelam, Kladney, Raleigh, Sun, Daokun, Perez-Castro, Antonio, Matondo, Ramadhan B., Nantasanti, Sathidpak, Mokry, Michal, Huang, Kun, Machiraju, Raghu, Fernandez, Soledad, Rosol, Thomas J., Coppola, Vincenzo, Pohar, Kamal S., Pipas, James M., Schmidt, Carl R., de Bruin, Alain, Leone, Gustavo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2016
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4966321/
https://ncbi.nlm.nih.gov/pubmed/27454291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI85506
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