The nonsense-mediated RNA decay pathway is disrupted in inflammatory myofibroblastic tumors

Inflammatory myofibroblastic tumors (IMTs) are characterized by myofibroblast proliferation and an inflammatory cell infiltrate. Little is known about the molecular pathways that precipitate IMT formation. Here, we report the identification of somatic mutations in UPF1, a gene that encodes an essent...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:J Clin Invest
Κύριοι συγγραφείς: Lu, JingWei, Plank, Terra-Dawn, Su, Fang, Shi, XiuJuan, Liu, Chen, Ji, Yuan, Li, ShuaiJun, Huynh, Andrew, Shi, Chao, Zhu, Bo, Yang, Guang, Wu, YanMing, Wilkinson, Miles F., Lu, YanJun
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Clinical Investigation 2016
Θέματα:
Brief Report
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4966300/
https://ncbi.nlm.nih.gov/pubmed/27348585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI86508
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