Emotional Impairment and Persistent Upregulation of mGlu(5) Receptor following Morphine Abstinence: Implications of an mGlu(5)-MOPr Interaction

BACKGROUND: A difficult problem in treating opioid addicts is the maintenance of a drug-free state because of the negative emotional symptoms associated with withdrawal, which may trigger relapse. Several lines of evidence suggest a role for the metabotropic glutamate receptor 5 in opioid addiction;...

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Detalles Bibliográficos
Publicado en:Int J Neuropsychopharmacol
Main Authors: Zanos, Panos, Georgiou, Polymnia, Gonzalez, Loreto Rojo, Hourani, Susanna, Chen, Ying, Kitchen, Ian, Kieffer, Brigitte L, Winsky-Sommerer, Raphaelle, Bailey, Alexis
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2016
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4966274/
https://ncbi.nlm.nih.gov/pubmed/26861145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyw011
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