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A retinoic acid receptor alpha antagonist selectively counteracts retinoic acid effects.

Retinoic acid (RA) exerts its pleiotropic effects on cell growth and differentiation through the activation of a family of transcription factors-the RA receptors (RARs). Three subtypes of these receptors exist, RAR alpha, RAR beta, and RAR gamma. The receptors are differentially expressed in differe...

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Autores principales: Apfel, C, Bauer, F, Crettaz, M, Forni, L, Kamber, M, Kaufmann, F, LeMotte, P, Pirson, W, Klaus, M
Formato: Artigo
Lenguaje:Inglês
Publicado: 1992
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC49659/
https://ncbi.nlm.nih.gov/pubmed/1323127
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