Co‐recruitment analysis of the CBL and CBLB signalosomes in primary T cells identifies CD5 as a key regulator of TCR‐induced ubiquitylation

T‐cell receptor (TCR) signaling is essential for the function of T cells and negatively regulated by the E3 ubiquitin–protein ligases CBL and CBLB. Here, we combined mouse genetics and affinity purification coupled to quantitative mass spectrometry to monitor the dynamics of the CBL and CBLB signali...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Syst Biol
Egile Nagusiak: Voisinne, Guillaume, García‐Blesa, Antonio, Chaoui, Karima, Fiore, Frédéric, Bergot, Elise, Girard, Laura, Malissen, Marie, Burlet‐Schiltz, Odile, Gonzalez de Peredo, Anne, Malissen, Bernard, Roncagalli, Romain
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2016
Gaiak:
Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4965873/
https://ncbi.nlm.nih.gov/pubmed/27474268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20166837
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