Quantitative interactomics in primary T cells unveils TCR signal diversification extent and dynamics

The activation of T cells by the T cell antigen receptor (TCR) results in the formation of signaling protein complexes (signalosomes), the composition of which has not been analyzed at systems-level. Here, we isolated primary CD4(+) T cells from 15 gene-targeted mice each expressing one tagged-form...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Nat Immunol
मुख्य लेखकों: Voisinne, Guillaume, Kersse, Kristof, Chaoui, Karima, Lu, Liaoxun, Chaix, Julie, Zhang, Lichen, Menoita, Marisa Goncalves, Girard, Laura, Ounoughene, Youcef, Wang, Hui, Burlet-Schiltz, Odile, Luche, Hervé, Fiore, Frédéric, Malissen, Marie, de Peredo, Anne Gonzalez, Liang, Yinming, Roncagalli, Romain, Malissen, Bernard
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2019
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6859066/
https://ncbi.nlm.nih.gov/pubmed/31591574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-019-0489-8
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