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T-cell immune adaptor SKAP1 regulates the induction of collagen-induced arthritis in mice

SKAP1 is an immune cell adaptor that couples the T-cell receptor with the ‘inside-out’ signalling pathway for LFA-1 mediated adhesion in T-cells. A connection of SKAP1 to the regulation of an autoimmune disorder has not previously been reported. In this study, we show that Skap1-deficient (skap1-/-)...

詳細記述

保存先:
書誌詳細
出版年:Immunol Lett
主要な著者: Smith, Xin, Taylor, Alison, Rudd, Christopher E.
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier/North-Holland Biomedical Press 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4965781/
https://ncbi.nlm.nih.gov/pubmed/27181093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imlet.2016.04.007
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