Immunogenicity of a novel tetravalent vaccine formulation with four recombinant lipidated dengue envelope protein domain IIIs in mice

We developed a novel platform to express high levels of recombinant lipoproteins with intrinsic adjuvant properties. Based on this technology, our group developed recombinant lipidated dengue envelope protein domain IIIs as vaccine candidates against dengue virus. This work aims to evaluate the immu...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Chiang, Chen-Yi, Pan, Chien-Hsiung, Chen, Mei-Yu, Hsieh, Chun-Hsiang, Tsai, Jy-Ping, Liu, Hsueh-Hung, Liu, Shih-Jen, Chong, Pele, Leng, Chih-Hsiang, Chen, Hsin-Wei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4965760/
https://ncbi.nlm.nih.gov/pubmed/27470096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30648
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