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Conformational Selection and Submillisecond Dynamics of the Ligand-binding Domain of the N-Methyl-d-aspartate Receptor

The N-methyl-d-aspartate (NMDA) receptors are heteromeric non-selective cation channels that require the binding of glycine and glutamate for gating. Based on crystal structures, the mechanism of partial agonism at the glycine-binding site is thought to be mediated by a shift in the conformational e...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Dolino, Drew M., Rezaei Adariani, Soheila, Shaikh, Sana A., Jayaraman, Vasanthi, Sanabria, Hugo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4965566/
https://ncbi.nlm.nih.gov/pubmed/27226581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.721274
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