Krüppel-like Factor 3 (KLF3/BKLF) Is Required for Widespread Repression of the Inflammatory Modulator Galectin-3 (Lgals3)

The Lgals3 gene encodes a multifunctional β-galactoside-binding protein, galectin-3. Galectin-3 has been implicated in a broad range of biological processes from chemotaxis and inflammation to fibrosis and apoptosis. The role of galectin-3 as a modulator of inflammation has been studied intensively,...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Knights, Alexander J., Yik, Jinfen J., Mat Jusoh, Hanapi, Norton, Laura J., Funnell, Alister P. W., Pearson, Richard C. M., Bell-Anderson, Kim S., Crossley, Merlin, Quinlan, Kate G. R.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2016
Subjects:
Gene Regulation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4965555/
https://ncbi.nlm.nih.gov/pubmed/27226561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.715748
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