Phosphorylation of Krüppel-like Factor 3 (KLF3/BKLF) and C-terminal Binding Protein 2 (CtBP2) by Homeodomain-interacting Protein Kinase 2 (HIPK2) Modulates KLF3 DNA Binding and Activity

Krüppel-like factor 3 (KLF3/BKLF), a member of the Krüppel-like factor (KLF) family of transcription factors, is a widely expressed transcriptional repressor with diverse biological roles. Although there is considerable understanding of the molecular mechanisms that allow KLF3 to silence the activit...

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Vydáno v:J Biol Chem
Hlavní autoři: Dewi, Vitri, Kwok, Alister, Lee, Stella, Lee, Ming Min, Tan, Yee Mun, Nicholas, Hannah R., Isono, Kyo-ichi, Wienert, Beeke, Mak, Ka Sin, Knights, Alexander J., Quinlan, Kate G. R., Cordwell, Stuart J., Funnell, Alister P. W., Pearson, Richard C. M, Crossley, Merlin
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2015
Témata:
Gene Regulation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375508/
https://ncbi.nlm.nih.gov/pubmed/25659434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.638338
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