Identification of a mammalian gene structurally and functionally related to the CDC25 gene of Saccharomyces cerevisiae.

The yeast Saccharomyces cerevisiae CDC25 gene encodes a nucleotide-exchange-factor (NEF) that can convert the inactive GDP-bound state of RAS proteins to an active RAS-GTP complex. CDC25 can activate the yeast RAS proteins as well as the human H-ras protein. CDC25 is a member of a family of yeast ge...

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Autores principales: Wei, W, Mosteller, R D, Sanyal, P, Gonzales, E, McKinney, D, Dasgupta, C, Li, P, Liu, B X, Broek, D
Formato: Artigo
Lenguaje:Inglês
Publicado: 1992
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC49653/
https://ncbi.nlm.nih.gov/pubmed/1379731
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