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The Saccharomyces cerevisiae CDC25 gene product binds specifically to catalytically inactive ras proteins in vivo.

Genetic data suggest that the yeast cell cycle control gene CDC25 is an upstream regulator of RAS2. We have been able to show for the first time that the guanine nucleotide exchange proteins Cdc25 and Sdc25 from Saccharomyces cerevisiae bind directly to their targets Ras1 and Ras2 in vivo. Using the...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Principais autores: Munder, T, Fürst, P
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1992
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364380/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1569942/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.5.2091-2099.1992
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