The Saccharomyces cerevisiae CDC25 gene product binds specifically to catalytically inactive ras proteins in vivo.

Genetic data suggest that the yeast cell cycle control gene CDC25 is an upstream regulator of RAS2. We have been able to show for the first time that the guanine nucleotide exchange proteins Cdc25 and Sdc25 from Saccharomyces cerevisiae bind directly to their targets Ras1 and Ras2 in vivo. Using the...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Munder, T, Fürst, P
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1992
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364380/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1569942/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.5.2091-2099.1992
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