Disruption of circadian regulation by brain grafts that overexpress Alzheimer beta/A4 amyloid.
Alzheimer disease patients exhibit irregularities in the patterns of normally circadian (daily) rhythms. Alzheimer-type pathology has been reported in the hypothalamus and in the suprachiasmatic nuclei, the putative site of the circadian oscillator. We examined the relationship between the neuropath...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1992
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49651/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1496005/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.15.7090 |
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