Genotype-Phenotype Associations of the CD-Associated Single Nucleotide Polymorphism within the Gene Locus Encoding Protein Tyrosine Phosphatase Non-Receptor Type 22 in Patients of the Swiss IBD Cohort

BACKGROUND: Protein tyrosine phosphatase non-receptor type 22 (PTPN22) plays an important role in immune cell function and intestinal homeostasis. The single nucleotide polymorphism (SNP) rs2476601 within the PTPN22 gene locus results in aberrant function of PTPN22 protein and protects from Crohn’s...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Spalinger, Marianne R., Zeitz, Jonas, Biedermann, Luc, Rossel, Jean-Benoit, Sulz, Michael C., Frei, Pascal, Scharl, Sylvie, Vavricka, Stephan R., Fried, Michael, Rogler, Gerhard, Scharl, Michael
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2016
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4964985/
https://ncbi.nlm.nih.gov/pubmed/27467733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160215
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