HLA-DR peptide occupancy can be regulated with a wide variety of small molecules

HLA-DR is the most commonly expressed and likely the most medically important human MHC class II, antigen presenting protein. In a normal immune response, HLA-DR binds to antigenic peptide and the HLA-DR/peptide complex binds to a T-cell receptor, thus contributing to T-cell activation and stimulati...

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Détails bibliographiques
Publié dans:Hum Vaccin Immunother
Auteurs principaux: Blazekovic, Francesca, Odukoya, Dana, Butler, Shanitra N., Mauro, James A., Ramsamooj, Michael, Puleo, Erika, Szekeres, Karoly, Dana, Dibyendu, Kumar, Sanjai, Ragupathi, Govind, Blanck, George
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2015
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4964726/
https://ncbi.nlm.nih.gov/pubmed/26453454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2015.1089370
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